Intramolecular cycloaddition of azomethine ylides in the preparation of pyrrolidino[2',3':3,4]pyrrolidino[1,2- a]benzimidazoles.
Intramolecular cycloaddition of azomethine ylides in the preparation of pyrrolidino[2',3':3,4]pyrrolidino[1,2- a]benzimidazoles.
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偶氮甲碱叶立德在制备吡咯烷[2,3:3,4]吡咯烷[1,2-a]苯并咪唑中的分子内环加成。
DOI:
10.1021/ol702301n
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发表时间:
2007
期刊:
影响因子:
5.2
通讯作者:
Kurth,MarkJ
中科院分区:
文献类型:
--
作者:
Meng,Liping;Fettinger,JamesC;Kurth,MarkJ
The parent pyrrolidino[2‘,3‘:3,4]pyrrolidino[1,2-a]benzimidazole heterocycle as well as a series of novel analogues have been synthesized utilizing a microwave-assisted intramolecular cycloaddition of azomethine ylides as the key transformation. A variety of diversity groups were added to explore the scope of this reaction and to provide a number of new compounds for biological screening.