Effects of diet and exercise in men and postmenopausal women with low levels of HDL cholesterol and high levels of LDL cholesterol
Effects of diet and exercise in men and postmenopausal women with low levels of HDL cholesterol and high levels of LDL cholesterol
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DOI：
10.1056/nejm199807023390103
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发表时间：
1998-07-02
影响因子：
158.5
通讯作者：
Wood, PD
中科院分区：
文献类型：
--
作者：
Stefanick, ML;Mackey, S;Wood, PD
国家胆固醇教育计划（NCEP）制定的指南促进运动和减肥，以治疗脂蛋白水平异常。然而，很少有人知道运动或NCEP饮食的影响，这是适度低脂肪和胆固醇，在脂蛋白水平的人，使他们在高风险的冠心病。方法我们研究了血浆脂蛋白水平在180绝经后妇女，45至64岁，和197名男子，30至64岁，高密度脂蛋白（HDL）胆固醇水平较低（女性低于或等于59 mg/dl，男性低于或等于44 mg/dl）和低密度脂蛋白（LDL）胆固醇水平中度升高（>125 mg/dl，但125 mg/dl，
Background Guidelines established by the National Cholesterol Education Program (NCEP) promote exercise and weight loss for the treatment of abnormal lipoprotein levels. Little is known, however, about the effects of exercise or the NCEP diet, which is moderately low in fat and cholesterol, in persons with lipoprotein levels that place them at high risk for coronary heart disease.Methods We studied plasma lipoprotein levels in 180 postmenopausal women, 45 through 64 years of age, and 197 men, 30 through 64 years of age, who had low high-density lipoprotein (HDL) cholesterol levels (less than or equal to 59 mg per deciliter in women and less than or equal to 44 mg per deciliter in men) and moderately elevated levels of low-density lipoprotein (LDL) cholesterol (>125 mg per deciliter but 125 mg per deciliter but