EVIDENCE OF RADIATION-INDUCED REDUCTION BF HEIGHT AND BODY-WEIGHT FROM REPEATED MEASUREMENTS OF ADULTS EXPOSED IN CHILDHOOD TO THE ATOMIC BOMBS
EVIDENCE OF RADIATION-INDUCED REDUCTION BF HEIGHT AND BODY-WEIGHT FROM REPEATED MEASUREMENTS OF ADULTS EXPOSED IN CHILDHOOD TO THE ATOMIC BOMBS
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DOI：
10.2307/3578576
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发表时间：
1994-10-01
影响因子：
3.4
通讯作者：
SCHULL, WJ
中科院分区：
文献类型：
--
作者：
OTAKE, M;FUJIKOSHI, Y;SCHULL, WJ
对受原子弹辐射影响的生长减缓情况进行了研究，研究对象是轰炸时年龄在10岁以下的人（ATB），并根据成人健康研究第4至第7周期（1964-1972年）检查过程中测量的身高和体重进行了生长曲线分析。正如预期的那样，最大的增长差异出现在男性和女性之间。然而，在可重复测量4次身高和体重的幸存者中，观察到与剂量相关的生长显著减少（DS 86）。对一个更广泛的数据集（n = 821）进行纵向分析，使用简单线性回归模型的预期值，拟合到254个缺失测量值的身高和体重的三个现有测量值集，也表明与辐射有关的生长显著减少。战后几年中营养不良和正常家庭生活中断等因素可能造成的影响难以评估，但对社会经济因素对分析这些数据的影响进行了讨论。
Reduction of growth from exposure to atomic bomb radiation has been examined using individuals under 10 years old at the time of the bombing (ATB) and a growth curve analysis based on measurements of height and weight made in the course of the 4th-7th cycles of the Adult Health Study examinations (1964-1972). As expected, the largest difference in growth to emerge is between males and females. However, a highly significant reduction of growth associated with dose (DS86) was observed among those survivors for whom four repeated measurements of height and weight were available. Longitudinal analysis of a more extended data set (n = 821), using expected values based on simple linear regression models fitted to the three available sets of measurements of height and weight on the 254 individuals with a missing measurement, also indicates a significant radiation-related growth reduction. The possible contribution of such factors as poor nutrition and disruption of normal family life in the years immediately after the war is difficult to evaluate, but the effects of socioeconomic factors on the analysis of these data are discussed.