The Gell-Coombs classification of hypersensitivity reactions: a re-interpretation

The Gell-Coombs classification of hypersensitivity reactions: a re-interpretation
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DOI:
10.1016/s1471-4906(03)00142-x
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发表时间:
2003-07-01
影响因子:
16.8
通讯作者:
Rajan, TV
Rajan, TV
中科院分区:
医学1区
文献类型:
--
作者:
Rajan, TV

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盖尔和库姆斯将超敏反应分为四种“类型”。我认为,这些反应代表“超敏反应”表现的前提是有限的,它们代表了身体用来对抗感染因子的四种主要策略。我进一步提出,在Gell和Coombs分类中没有预见到的第五种策略。
Gell and Coombs classified hypersensitivity reactions into four 'types'. I suggest that the premise that these reactions represent 'hypersensitivity' manifestations is limiting and that they represent four major strategies that the body uses to combat infectious agents. I further propose that there is a fifth strategy that was not envisioned in the Gell and Coombs classification.