Change in health-related quality of life and functional disability over time post-concussion in youth.
Change in health-related quality of life and functional disability over time post-concussion in youth.
复制标题
青少年脑震荡后随时间的推移，与健康相关的生活质量和功能障碍发生变化。
DOI：
10.1007/s11136-023-03480-4
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发表时间：
2023
期刊：
影响因子：
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通讯作者：
Yang,Jingzhen
中科院分区：
文献类型：
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作者：
Recker,Robyn;Alshaikh,Enas;Kaur,Archana;Yeates,KeithOwen;Yang,Jingzhen
目的脑震荡对儿童的认知、情感、行为和/或社会功能都有不利影响。我们试图检查从损伤前到脑震荡后1周的健康相关生活质量（HRQOL）和功能障碍的变化，以及11-17岁脑震荡青年的症状缓解。MethodsIn this prospective，longitudinal cohort study，83例脑震荡青年，年龄11-17岁，每天自我报告脑震荡后症状以及基线HRQOL和功能障碍。（损伤前，回顾性）、脑震荡后1周和症状缓解。我们使用分段线性混合模型，调整潜在的协变量，对从损伤前到脑震荡后1周以及从脑震荡后1周到症状缓解的总体和子量表HRQOL和功能残疾评分随时间的变化进行建模。估计固定效应与相应的调整系数（β），沿着，其95%的置信区间presented.ResultsOverall HRQOL恶化，从损伤前到损伤后1周（β=-5.40，95%CI-9.22，-1.58），但没有改变，从1周损伤后症状的解决。从伤前到伤后1周，身体HRQOL恶化（β= − 9.90，95%CI − 14.65，− 5.14），但从伤后1周到症状缓解有所改善（β= 1.64，95%CI 0.50，2.78），而心理社会HRQOL没有随时间变化。功能障碍从伤前到伤后1周恶化（β= 8.36，95%CI 5.93，10.79），但从伤后1周到症状缓解无变化。症状持续时间> 14天的青年报告较差的HRQOL和功能残疾比那些谁恢复≤ 14天，更大的每日脑震荡后症状评分与较差的HRQOL和功能disability.ConclusionConcussions有负面影响的整体和身体HRQOL和功能残疾的青年急性损伤后。HRQOL评分可用于告知临床治疗决策，以协助恢复过程。
PurposeConcussions can have detrimental on children’s cognitive, emotional, behavioral, and/or social functioning. We sought to examine changes in health-related quality of life (HRQOL) and functional disability from pre-injury to 1-week post-concussion, and to symptom resolution among youth ages 11–17 with a concussion.MethodsIn this prospective, longitudinal cohort study, 83 concussed youth, ages 11–17, self-reported post-concussion symptoms daily as well as HRQOL and functional disability at baseline (pre-injury, retrospective), 1-week post-concussion, and symptom resolution. We modeled changes in overall and sub-scale HRQOL and functional disability scores over time from pre-injury to 1-week post-concussion and from 1-week post-concussion to symptom resolution using a piecewise linear mixed model, adjusting for potential covariables. Estimated fixed effects with a corresponding adjusted coefficient (beta), along with their 95% confidence intervals are presented.ResultsOverall HRQOL worsened from pre-injury to 1-week post-injury (β= − 5.40, 95%CI − 9.22, − 1.58) but did not change from 1-week post-injury to symptom resolution. Physical HRQOL worsened from pre-injury to 1-week post-injury (β= − 9.90, 95%CI − 14.65, − 5.14) but improved from 1-week post-injury to symptom resolution (β= 1.64, 95%CI 0.50, 2.78), while psychosocial HRQOL showed no change over time. Functional disability worsened from pre-injury to 1-week post-injury (β= 8.36, 95%CI 5.93, 10.79) but with no change from 1-week post-injury to symptom resolution. Youth with symptom duration > 14 days reported worse HRQOL and functional disability than those who recovered in ≤ 14 days and greater daily post-concussion symptom scores were associated with worse HRQOL and functional disability.ConclusionConcussions have a negative impact on overall and physical HRQOL and functional disability in youth acutely post-injury. Ratings of HRQOL could be used to inform clinical treatment decisions to assist with the recovery process.