Effects of sidechain isomerism on polymer-based non-covalent protein delivery
Effects of sidechain isomerism on polymer-based non-covalent protein delivery
复制标题
侧链异构对基于聚合物的非共价蛋白质递送的影响
DOI:
10.1039/d2cc02343a
复制
发表时间:
2022
影响因子:
4.9
通讯作者:
Moon, Joong Ho
中科院分区:
文献类型:
--
作者:
Barrios, Alfonso;Milan, Mario;Perozo, Elianny;Hossen, Md Lokman;Chapagain, Prem;Moon, Joong Ho
We present the importance of functional group isomerism on intracellular protein delivery using polymers containing different isomeric side chains. While the physical properties of polymer/protein complexes are relatively similar, different planarity of the isomers greatly influences the cellular entry efficiency.