Effects of sidechain isomerism on polymer-based non-covalent protein delivery

Effects of sidechain isomerism on polymer-based non-covalent protein delivery
复制标题

侧链异构对基于聚合物的非共价蛋白质递送的影响

DOI:
10.1039/d2cc02343a
复制
发表时间:
2022
影响因子:
4.9
通讯作者:
Moon, Joong Ho
Moon, Joong Ho
中科院分区:
化学2区
文献类型:
--
作者:
Barrios, Alfonso;Milan, Mario;Perozo, Elianny;Hossen, Md Lokman;Chapagain, Prem;Moon, Joong Ho

文献摘要

相似文献

我们提出了官能团异构对使用含有不同异构侧链的聚合物进行细胞内蛋白质递送的重要性。虽然聚合物/蛋白质复合物的物理性质相对相似,但异构体的不同平面度极大地影响了细胞进入效率。
We present the importance of functional group isomerism on intracellular protein delivery using polymers containing different isomeric side chains. While the physical properties of polymer/protein complexes are relatively similar, different planarity of the isomers greatly influences the cellular entry efficiency.