ANATOMIC VALIDATION OF LEFT-VENTRICULAR MASS ESTIMATES FROM CLINICAL TWO-DIMENSIONAL ECHOCARDIOGRAPHY - INITIAL RESULTS
ANATOMIC VALIDATION OF LEFT-VENTRICULAR MASS ESTIMATES FROM CLINICAL TWO-DIMENSIONAL ECHOCARDIOGRAPHY - INITIAL RESULTS
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DOI：
10.1161/01.cir.67.2.348
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发表时间：
1983-01-01
期刊：
影响因子：
37.8
通讯作者：
WEBER, KT
中科院分区：
文献类型：
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作者：
REICHEK, N;HELAK, J;WEBER, KT
进行了一项前瞻性解剖验证研究，以确定临床二维超声心动图（2-D回声）研究中左心室（LV）质量估计的准确性。在21例受试者中，将死前二维超声心动图左心室质量测定结果与死后室壁解剖左心室重量进行了比较。主要心脏诊断包括解剖左室动脉瘤4例，二尖瓣狭窄切除术后状态1例，透壁性心肌梗死7例，充血性心肌病5例，风湿性二尖瓣病变2例，慢性重度二尖瓣或主动脉瓣返流3例，淀粉样心脏2例，正常心脏3例。11例患者存在明显的右心扩张，4例患者存在LV血栓。根据短轴、面积-长度方法，使用每个2-D回波仪器在体外导出的回归方程来校正LV质量估计：未校正的LV质量= 1.055 ×泰晤士报5/6（AtLt-AcLc）+ B，其中At =高乳头肌水平的总短轴LV图像面积，Lc =左心室内膜长度，k =仪器特定回归斜率，B =仪器特定截距。二维超声心动图的左心室质量与实际左心室重量的相关性非常好（r = 0.93，斜率= 0.85，SEE [估计的标准误差] = 31 g，范围77-454 g）。在这些明显扭曲的心脏中，M型超声心动图LV质量估计值不太可靠（r = 0.86，SEE = 59 g）。这些2-D超声心动图LV质量结果与双平面血管造影和M型超声心动图在更对称心脏中的报告结果相比更为有利。回归校正的二维超声心动图可能是确定人体左室质量的首选方法。
A prospective anatomic validation study was performed to determine the accuracy of left ventricular (LV) mass estimates from clinical 2-dimensional echocardiographic (2-D echo) studies. In 21 subjects, antemortem 2-D echo LV mass determinations were compared with anatomic LV weight by postmortem chamber dissection. Major cardiac diagnoses included anatomic LV aneurysm in 4, status post-aneurysmectomy in 1, transmural myocardial infarction in 7, congestive cardiomyopathy in 5, rheumatic mitral disease in 2, chronic severe mitral or aortic regurgitation in 3, amyloid heart in 2 and normal heart in 3. Marked right-heart dilatation was present in 11 patients and LV thrombus in 4. Regression equations derived in vitro for each 2-D echo instrument were used to correct LV mass estimates based on a short-axis, area-length method: uncorrected LV mass = 1.055 .times. k .times. 5/6 (AtLt - AcLc) + b, where At = total short-axis LV image area at the high papillary muscle level, Lc = endocardial LV length, k = an instrument-specific regression slope and b = an instrument-specific intercept. LV mass by 2-D echo correlated extremely well with actual LV weight (r = 0.93 slope = 0.85, SEE [standard error of estimate] = 31 g, range 77-454 g). M-mode echocardiographic LV mass estimates were less reliable (r = 0.86, SEE = 59 g) in these markedly distorted hearts. These 2-D echo LV mass results compare favorably with reported results from biplane angiography and M-mode echocardiography in more symmetric hearts. Regression-corrected 2-D echo may be the method of choice for determining LV mass in man.