Effects of exercise on cardiovascular risk factors in type 2 diabetes: a meta-analysis.
Effects of exercise on cardiovascular risk factors in type 2 diabetes: a meta-analysis.
复制标题
DOI：
10.2337/dc10-1881
复制
发表时间：
2011-05
期刊：
影响因子：
16.2
通讯作者：
Petrella RJ
中科院分区：
文献类型：
--
作者：
Chudyk A;Petrella RJ
运动是糖尿病管理和预防糖尿病的基石。然而，运动方式对 2 型糖尿病心血管 (CV) 危险因素的影响尚不清楚。我们对 1970 年至 2009 年 10 月期间代表性数据库中的文献进行了系统回顾，探讨有氧运动或抗阻运动训练对 CV 风险临床标志物的影响，包括 2 型糖尿病患者的血糖控制、血脂异常、血压和身体成分。在检索到的 645 篇文章中，有 34 篇符合我们的纳入标准；大多数人调查了单独的有氧运动，10 人报告了联合运动训练。单独有氧运动或与阻力训练 (RT) 相结合，分别显着改善 HbA1c -0.6 和 -0.67%（95% CI 分别为 -0.98 至 -0.27 和 -0.93 至 -0.40），收缩压 (SBP) 分别为 -6.08 和 -3.59 mmHg（95% CI -10.79 至 -1.36 和 -6.93 -0.24），甘油三酯 -0.3 mmol/L（95% CI 分别为 -0.48 至 -0.11 和 -0.57 至 -0.02）。有氧运动和抗阻运动相结合，腰围显着改善-3.1厘米（95% CI -10.3至-1.2），尽管在后两个标记中观察到的研究较少且反应异质性较大。单独进行抗阻运动或与任何其他形式的运动相结合，并未发现对 CV 指标有任何显着影响。单独进行有氧运动或与 RT 相结合可改善血糖控制、收缩压、甘油三酯和腰围。单独进行抗阻运动对 2 型糖尿病心血管风险标志物的影响尚不清楚。
Exercise is a cornerstone of diabetes management and the prevention of incident diabetes. However, the impact of the mode of exercise on cardiovascular (CV) risk factors in type 2 diabetes is unclear. We conducted a systematic review of the literature between 1970 and October 2009 in representative databases for the effect of aerobic or resistance exercise training on clinical markers of CV risk, including glycemic control, dyslipidemia, blood pressure, and body composition in patients with type 2 diabetes. Of 645 articles retrieved, 34 met our inclusion criteria; most investigated aerobic exercise alone, and 10 reported combined exercise training. Aerobic alone or combined with resistance training (RT) significantly improved HbA1c −0.6 and −0.67%, respectively (95% CI −0.98 to −0.27 and −0.93 to −0.40, respectively), systolic blood pressure (SBP) −6.08 and −3.59 mmHg, respectively (95% CI −10.79 to −1.36 and −6.93 to −0.24, respectively), and triglycerides −0.3 mmol/L (95% CI −0.48 to −0.11 and −0.57 to −0.02, respectively). Waist circumference was significantly improved −3.1 cm (95% CI −10.3 to −1.2) with combined aerobic and resistance exercise, although fewer studies and more heterogeneity of the responses were observed in the latter two markers. Resistance exercise alone or combined with any other form of exercise was not found to have any significant effect on CV markers. Aerobic exercise alone or combined with RT improves glycemic control, SBP, triglycerides, and waist circumference. The impact of resistance exercise alone on CV risk markers in type 2 diabetes remains unclear.