Photoswitched DNA-binding of a photochromic spiropyran
Photoswitched DNA-binding of a photochromic spiropyran
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DOI：
10.1021/ja801968f
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发表时间：
2008-09-10
影响因子：
15
通讯作者：
Andreasson, Joakim
中科院分区：
文献类型：
--
作者：
Andersson, Johanna;Li, Shiming;Andreasson, Joakim
The dramatically different DNA-binding properties of the two isomeric forms of a photochromic spiropyran have been demonstrated, enabling photoswitched DNA binding. The closed, UV-absorbing form shows no signs of interaction with DNA. Upon UV exposure the spiropyran is isomerized to the open form that binds to DNA by intercalation. The process is fully reversible as the corresponding dissociation process is induced by visible light.
