CAPSAICIN-SENSITIVE VAGAL AFFERENT NEURONS INNERVATING THE RAT PANCREAS

CAPSAICIN-SENSITIVE VAGAL AFFERENT NEURONS INNERVATING THE RAT PANCREAS
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DOI:
10.1016/0304-3940(87)90597-0
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发表时间:
1987-06-01
影响因子:
2.5
通讯作者:
CAROBI, C
CAROBI, C
中科院分区:
医学4区
文献类型:
--
作者:
CAROBI, C

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采用经胆总管注入胰腺的辣根过氧化物酶(HRP)轴突逆行转运的方法研究了大鼠胰腺迷走神经传入神经的分布。右侧和左侧结节神经节可见许多标记神经元体。观察结状神经节中标记神经元群的大小分布,并与辣椒素预处理大鼠进行比较。在用辣椒素治疗的新生大鼠中,最小的神经元(高达200.mu)。2、3类(200 ~ 300,300 ~ 400.mu)完全缺失。M2)均减少。
The vagal afferent innervation of the rat pancreas was investigated by the use of retrograde axonal transport of horseradish peroxidase (HRP) injected into the pancreas through the common bile duct. Many labeled neuronal somata were found in the right and left nodose ganglia. The size distribution of the labeled neuronal population in the nodose ganglia was examined and compared with that obtained from rats pretreated with capsaicin. In rats treated neonatally with capsaicin the smallest neurons (up to 200 .mu.m2) were completely absent and those belonging to the second and third classes (200-300, 300-400 .mu.m2) were reduced in both vagi.