Diabetes-related change in physical disability from midlife to older adulthood: Evidence from 1996-2003 Survey of Health and Living Status of the Elderly in Taiwan
Diabetes-related change in physical disability from midlife to older adulthood: Evidence from 1996-2003 Survey of Health and Living Status of the Elderly in Taiwan
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DOI：
10.1016/j.diabres.2010.12.003
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发表时间：
2011-03-01
影响因子：
5.1
通讯作者：
Ofstedal, Mary Beth
中科院分区：
文献类型：
--
作者：
Chiu, Ching-Ju;Wray, Linda A.;Ofstedal, Mary Beth
在台湾，五分之一的老年人被诊断患有糖尿病。本研究以1996-2003年台湾老年人健康与生活状况调查（SHLSET）中5121名具有全国代表性的中老年人为研究对象。通过采用队列序贯设计和多水平模型，它结合了横截面和纵向证据来描述从中年到老年的身体残疾的年龄轨迹，并辨别糖尿病对该轨迹变化的贡献程度。在完全控制的模型中，糖尿病和糖尿病x年龄相互作用的主要影响提供了证据，表明糖尿病独立且持续地改变台湾成年人的身体功能，超过自然衰老过程。此外，虽然在身体残疾的年龄轨迹中添加糖尿病分别解释了身体残疾轨迹水平和线性变化的3.2%和1.6%的方差，但进一步添加随访状态，社会人口因素和合并症共解释了该轨迹水平和线性变化的40.5%和29.1%的方差。这些结果意味着，预防糖尿病相关合并症的发生可能会减少身体残疾水平和变化率的恶化。出版社：Elsevier爱尔兰Ltd.
One in five older adults in Taiwan have been diagnosed with diabetes. This study drew on disability data for 5121 nationally representative middle-aged and older adults from the 1996-2003 Survey of Health and Living Status of the Elderly in Taiwan (SHLSET). By employing cohort sequential design and multilevel models, it combined cross-sectional and longitudinal evidence to characterize the age trajectory of physical disability from midlife to older adulthood and to discern the extent to which diabetes contributes to the variation in that trajectory. The main effects of diabetes and diabetes x age interaction in the fully controlled model provide evidence that diabetes independently and consistently changes physical functioning over and above natural aging processes in Taiwanese adults. In addition, while adding diabetes in the age trajectory of physical disability explained 3.2% and 1.6% of the variance in levels of and linear changes in physical disability trajectory, respectively, further adding follow-up status, sociodemographic factors and comorbidities altogether explained 40.5% and 29.1% of the variance in levels of and linear changes in that trajectory. These results imply that preventing the incidence of diabetes-related comorbidities may reduce the deterioration in both levels of and rates of change in physical disability. Published by Elsevier Ireland Ltd.