Cold Panniculitis

Cold Panniculitis
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DOI:
10.1016/j.det.2008.05.015
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发表时间:
2008-10-01
影响因子:
2.4
通讯作者:
Casado-Jimenez, Mariano
Casado-Jimenez, Mariano
中科院分区:
医学2区
文献类型:
--
作者:
Quesada-Cortes, Alicia;Campos-Munoz, Lucia;Casado-Jimenez, Mariano

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冷脂膜炎已被描述在儿童和年轻妇女冷暴露后。组织病理学上,冷性脂膜炎表现为小叶性脂膜炎,由脂肪小叶内淋巴细胞和组织细胞浸润组成。通常,真皮显示主要由淋巴细胞组成的浅表和深部血管周围浸润,无血管炎。炎症在真皮-皮下交界处最强烈。冷性脂膜炎的鉴别诊断应建立在新生儿皮下脂肪坏死、硬肿症、类固醇后脂膜炎、冻疮和冻伤。
Cold panniculitis has been described in children and young women following cold exposure. Histopathologically, cold panniculitis shows a mostly lobular panniculitis, which consists of an infiltrate of lymphocytes and histiocytes in the fat lobules. Usually, the dermis shows a superficial and deep perivascular infiltrate mostly composed of lymphocytes, with no vasculitis. Inflammation is most intense at the dermal-subcutaneous junction. Differential diagnosis of cold panniculitis should be established with subcutaneous fat necrosis of the newborn, sclerema neonatorum, poststeroid panniculitis, chilblains, and frostbites.