Analysis of donor-type chimerism in lineage-specific cell populations after allogeneic myeloablative and nonmyeloablative stem cell transplantation
Analysis of donor-type chimerism in lineage-specific cell populations after allogeneic myeloablative and nonmyeloablative stem cell transplantation
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DOI：
10.1038/sj.bmt.1705352
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发表时间：
2006-05-01
影响因子：
4.8
通讯作者：
Imamura, M
中科院分区：
文献类型：
--
作者：
Miura, Y;Tanaka, J;Imamura, M
我们分析了36例接受常规强度异基因造血干细胞移植（CST）和34例接受非清髓性异基因造血干细胞移植（NST）治疗恶性血液病的患者的CD3+、CD14.15+和CD56+细胞的供体型嵌合体。在移植后第28天，接受非全身照射（TBI）方案的NST患者的所有组分和CST患者的CD 3+细胞显示更频繁的混合嵌合体（
We analyzed donor-type chimerism in CD3+, CD14.15+ and CD56+ cells from 36 patients who had undergone conventional-intensity allogeneic stem cell transplantation ( CST) and 34 patients who had undergone nonmyeloablative allogeneic stem cell transplantation ( NST) for hematological malignancies. On day 28 after transplantation, all fractions in NST patients and CD3+ cells in CST patients who received a non-total body irradiation ( TBI) regimen showed more frequent mixed chimerism (