Kinesin: the tail unfolds

Kinesin: the tail unfolds
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DOI:
10.1038/12947
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发表时间:
1999-09-01
影响因子:
21.3
通讯作者:
Scholey, J
Scholey, J
中科院分区:
生物学1区
文献类型:
--
作者:
Cross, R;Scholey, J

文献摘要

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The cargo-binding tail of the motor protein kinesin acts as a regulator of kinesin-driven vesicle transport. In the absence of bound cargo, the kinesin tail interacts with the motor domains and inhibits their activity. Cargo binding blocks this interaction and relieves the inhibition.