Unique allelic restriction fragments of the human Ha-ras locus in leukocyte and tumour DNAs of cancer patients
Unique allelic restriction fragments of the human Ha-ras locus in leukocyte and tumour DNAs of cancer patients
复制标题
癌症患者白细胞和肿瘤 DNA 中人类 Ha-ras 位点的独特等位基因限制片段
作者：
T. Krontiris;N. DiMartino;M. Colb;D. Parkinson
来自癌症患者的白色血细胞DNA和来自肿瘤和肿瘤衍生细胞系的DNA经常显示未在未受影响的人群中发现的Harvey ras癌基因位点的等位基因限制性片段。这种不寻常的等位基因的存在可能与癌症的易感性有关。
White blood cell DNA from cancer patients and DNA from tumours and tumour-derived cell lines frequently demonstrated allelic restriction fragments of the Harvey ras oncogene locus not found in the unaffected population. The presence of such unusual alleles may be linked to susceptibility to cancer.