Acceptance of repeat population-based voluntary counselling and testing for HIV in rural Malawi.

Acceptance of repeat population-based voluntary counselling and testing for HIV in rural Malawi.
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DOI:
10.1136/sti.2008.030320
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发表时间:
2009-04
影响因子:
3.6
通讯作者:
Kohler HP
Kohler HP
中科院分区:
医学2区
文献类型:
--
作者:
Obare F;Fleming P;Anglewicz P;Thornton R;Martinson F;Kapatuka A;Poulin M;Watkins S;Kohler HP

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审查马拉维农村地区对重复人群艾滋病毒自愿咨询和检测(VCT)的接受情况。行为和生物标记物数据是在2004年和2006年从大约3000名成年受访者中收集的。2004年,收集了口腔拭子样本,并使用酶联免疫吸附试验和确证的Western印迹试验进行了分析,而在2006年进行了指刺快速试验。我们使用χ2检验和比例显著性检验的交叉表来确定不同年份、个体特征和艾滋病毒风险在接受自愿咨询治疗方面的差异的统计学意义。首先,每一轮都有超过90%的受访者接受了艾滋病毒检测,尽管检测方案各有不同。其次,获得检测结果的个人比例从2004年的67%显著增加到2006年的98%,当时在采集样本几周后在随机选择的地点提供结果。第三,尽管那些成功接受第二次艾滋病毒检测的人的社会人口学和行为特征存在显著差异,但接受重复VCT的人情况并非如此。这表明,重复测试成功与否的差异可能来自与个体的联系,而不是接受测试或知道结果。在马拉维农村地区,由来自当地以外的训练有素的医护人员用唾液或血液在家中重复进行艾滋病毒检测几乎是普遍可以接受的,因此,在类似的情况下也可能是可以接受的。
To examine the acceptance of repeat population-based voluntary counselling and testing (VCT) for HIV in rural Malawi. Behavioural and biomarker data were collected in 2004 and 2006 from approximately 3000 adult respondents. In 2004, oral swab specimens were collected and analysed using ELISA and confirmatory Western blot tests, while finger-prick rapid testing was done in 2006. We used cross-tabulations with χ2 tests and significance tests of proportions to determine the statistical significance of differences in acceptance of VCT by year, individual characteristics and HIV risk. First, over 90% of respondents in each round accepted the HIV test, despite variations in testing protocols. Second, the percentage of individuals who obtained their test results significantly increased from 67% in 2004, when the results were provided in randomly selected locations several weeks after the specimens were collected, to 98% in 2006 when they were made available immediately within the home. Third, whereas there were significant variations in the sociodemographic and behavioural profiles of those who were successfully contacted for a second HIV test, this was not the case for those who accepted repeat VCT. This suggests that variations in the success of repeat testing might come from contacting the individuals rather than from accepting the test or knowing the results. Repeat HIV testing at home by trained healthcare workers from outside the local area, and with either saliva or blood, is almost universally acceptable in rural Malawi and, thus, likely to be acceptable in similar contexts.
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