Design and Development of Robust, Daylight-Activated, and Rechargeable Biocidal Polymeric Films as Promising Active Food Packaging Materials.
Design and Development of Robust, Daylight-Activated, and Rechargeable Biocidal Polymeric Films as Promising Active Food Packaging Materials.
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DOI：
10.1021/acsabm.3c00265
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发表时间：
2023-06
影响因子：
4.7
通讯作者：
S. Islam;Zheng Zhang;Cunyi Zhao;Nicharee Wisuthiphaet;N. Nitin;Gang Sun
中科院分区：
文献类型：
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作者：
S. Islam;Zheng Zhang;Cunyi Zhao;Nicharee Wisuthiphaet;N. Nitin;Gang Sun
新兴的传染病已经产生了一个主要的实际需求，即开发具有持久抗菌和抗病毒特性的食品工业活性包装材料。为了满足这一需求，开发适用于食品接触表面的新技术是非常必要的，但具有挑战性。维生素K（VK）衍生物的光活性特性的最近发现已经引起了很大的期望，因为这些化合物产生杀生物活性氧（ROS），所以它们作为功能膜开发中有希望的候选物。受光稳定的VK衍生物之一甲萘醌（VK 3）在可见光照射下的优异光活性的启发，我们展示了通过将VK 3掺入聚（乙烯-共-乙酸乙烯酯）（伊娃）基质中来制造日光介导的生物杀灭包装材料的方案。VK 3（即，1-5% w/w）掺入的伊娃薄膜成功证明了在日光暴露条件下分别产生活性氧以及针对大肠杆菌、无害李斯特菌和T7噬菌体的抗菌和抗病毒性能。结果表明，添加适量的VK 3可显著提高薄膜的活性氧产生率，并在薄膜上产生新的日光诱导的微生物杀灭性能。该薄膜的杀菌功能是持久的，并且在反复暴露于光时可再充电，使其成为替代目前可用的传统包装薄膜的可行竞争者。
The emerging infectious diseases have created one of the major practical needs to develop active packaging materials with durable antibacterial and antiviral properties for the food industry. To meet this demand, the development of new technologies applicable to food contact surfaces is highly desired but challenging. The recent discovery of the photoactive properties of vitamin K (VK) derivatives has raised great expectations as promising candidates in functional film development due to the generation of biocidal reactive oxygen species (ROS) by these compounds. Inspired by the excellent photoactivity of one of the light-stable VK derivatives, menadione (VK3), under visible daylight irradiation, we demonstrate a protocol for the fabrication of daylight-mediated biocidal packaging materials by incorporating VK3 into a poly (ethylene-co-vinyl acetate) (EVA) matrix. The VK3 (i.e., 1-5% w/w) incorporated EVA films successfully demonstrated the production of ROS and antibacterial and antiviral performance against Escherichia coli, Listeria innocua, and T7 bacteriophage, respectively, under daylight exposure conditions. The results revealed that the addition of a proper percentage of VK3 significantly enhanced the ROS productivity of the films and created a novel daylight-induced microbial killing performance on the films. The biocidal functions of the films are long-lasting and rechargeable when exposed to light repeatedly, making them a viable contender for replacing currently available conventional packaging films.