Massive Localized Lymphedema Revisited A Quickly Rising Complication of the Obesity Epidemic
Massive Localized Lymphedema Revisited A Quickly Rising Complication of the Obesity Epidemic
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DOI：
10.1097/sap.0b013e31828bb332
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发表时间：
2015-01-01
影响因子：
1.5
通讯作者：
Singh, Devinder P.
中科院分区：
文献类型：
--
作者：
Chopra, Karan;Tadisina, Kashyap K.;Singh, Devinder P.
大规模局限性淋巴水肿（MLL）是肥胖流行的一个上升和潜在致命的并发症。MLL被描述为肥胖患者的良性淋巴增生性过度生长，是一种继发性淋巴水肿，由淋巴流阻塞引起，具有特征性的临床和组织学表现。患者有大肿块，伴有典型的皮肤变化，常伴有淋巴哭泣，需要复杂的重建。虽然MLL通常是良性的，但如果不及时治疗，MLL可能发展为血管肉瘤，这进一步支持了对MLL及其后遗症进行更多研究的必要性。我们报告了一例独特的耻骨部MLL病例，患者为52岁男性，体重指数为75.7 kg/ m。全面回顾文献，共报道65例MLL病例，其中9例发生血管肉瘤（占全部病例的10.3%），6例死亡（占全部病例的9.2%）。我们发现女性优势为1.24:1，平均体重183 kg，以大腿为主，占48.5%。
Massive localized lymphedema (MLL) is a rising and potentially fatal complication of the obesity epidemic. Described as a benign lymphoproliferative overgrowth of obese patients, MLL is a form of secondary lymphedema, caused by the obstruction of lymphatic flow, with characteristic clinical and histological presentation. Patients have a large mass with classic skin changes often accompanied by lymphatic weeping that require complex reconstruction. Although oftentimes benign, if left untreated, MLL can progress to angiosarcoma, further supporting the need for more research into MLL and its sequelae. We present a unique case of MLL of the mons pubis in a 52-year-old man with a body mass index of 75.7 kg/ m(2). The literature was comprehensively reviewed with a total of 65 cases of MLL being described, 9 of which resulted in angiosarcoma (10.3% of all cases), 6 of which resulted in death (9.2% of all cases). We found a female predominance of 1.24 to 1, an average weight of 183 kg, and a 48.5% majority of cases in the thigh.