A new proteinaceous factor participating in the rat ejaculate coagulation--identification, isolation and function.
A new proteinaceous factor participating in the rat ejaculate coagulation--identification, isolation and function.
复制标题
一种参与大鼠射精凝固的新蛋白质因子的鉴定、分离和功能.
DOI：
10.1095/biolreprod26.5.875
复制
发表时间：
1982
影响因子：
3.6
通讯作者：
S. Milković
中科院分区：
文献类型：
--
作者：
E. Schön;J. Lukáč;S. Milković
已鉴定并分离出一种与大鼠精囊分泌物的碱性蛋白发生反应的蛋白质物质，该蛋白质存在于血清、睾丸和附睾匀浆以及未清洗的精子中。该蛋白质部分源自睾丸，其在男性血清、睾丸和附睾中的浓度取决于年龄，并且在性成熟男性中最高。去势后，其在男性血清中的浓度下降约 15%，与同龄女性血清中的浓度相当。附睾精子上存在的这种尚未被认识的蛋白质（分子量估计为 163000）对于大鼠精囊蛋白质的体外凝固是必需的。
A protein substance reacting with basic protein of rat seminal vesicle secretion, present in serum, testicular and epididymal homogenates and on unwashed spermatozoa, has been identified and isolated. The protein is partly of testicular origin, its concentration in male sera, testes and epididymides being age dependent and highest in sexually mature males. After castration, its concentration in male sera fails about 15%, to a comparable value present in female sera of the same age. The presence of this, as yet unrecognized, protein (molecular weight estimated at 163000) on epididymal spermatozoa is necessary for the in vitro coagulation of rat seminal vesicle proteins.