The Fine-Scale Functional Correlation of Striate Cortex in Sighted and Blind People
The Fine-Scale Functional Correlation of Striate Cortex in Sighted and Blind People
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DOI：
10.1523/jneurosci.0363-13.2013
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发表时间：
2013-10-09
影响因子：
5.3
通讯作者：
Aguirre, Geoffrey K.
中科院分区：
文献类型：
--
作者：
Butt, Omar H.;Benson, Noah C.;Aguirre, Geoffrey K.
To what extent are spontaneous neural signals within striate cortex organized by vision? We examined the fine-scale pattern of striate cortex correlations within and between hemispheres in rest-state BOLD fMRI data from sighted and blind people. In the sighted, we find that corticocortico correlation is well modeled as a Gaussian point-spread function across millimeters of striate cortical surface, rather than degrees of visual angle. Blindness produces a subtle change in the pattern of fine-scale striate correlations between hemispheres. Across participants blind before the age of 18, the degree of pattern alteration covaries with the strength of long-range correlation between left striate cortex and Broca's area. This suggests that early blindness exchanges local, vision-driven pattern synchrony of the striate cortices for long-range functional correlations potentially related to cross-modal representation.
