Barriers to Clinical Research Participation Among African Americans
Barriers to Clinical Research Participation Among African Americans
复制标题
DOI：
10.1177/1043659615575578
复制
发表时间：
2016-09-01
影响因子：
2.1
通讯作者：
Perez, Amelia
中科院分区：
文献类型：
--
作者：
Luebbert, Rebecca;Perez, Amelia
临床研究需要代表不同种族和民族的参与者，以准确地代表一般人群。非洲裔美国人的总体预期寿命比美国普通人口短。与美国其他种族相比，非洲裔美国人的高血压、中风、肥胖和糖尿病发病率较高，与中风和癌症相关的死亡率也较高。尽管非裔美国人之间存在许多健康差异，但他们在临床研究中的代表性不足。本文概述了可能影响非裔美国人参与临床研究的障碍。信任、实验、沟通和物流问题是最常见的障碍。在这次审查中确定的障碍和促进因素可能是有用的招聘和研究战略的发展和实施，是文化上敏感的，并可能提高信任和参与非裔美国人之间的意愿。
Clinical research requires representation of racially and ethnically diverse participants to accurately represent the general population. Overall life expectancy of African Americans is shorter than that of the general U.S. population. Compared with the other ethnic groups in the United States, African Americans have higher rates of hypertension, stroke, obesity, and diabetes, and higher rates of mortality related to stroke and cancer. Although many health disparities exist among African Americans, they are well underrepresented in clinical research. This article provides an overview of barriers that may influence participation in clinical research among African Americans. Issues of trust, experimentation, communication, and logistics are the most commonly identified barriers. The barriers and facilitators identified in this review may be useful in the development and implementation of recruitment and research strategies that are culturally sensitive and that may enhance trust and willingness to participate among African Americans.