Successful transporter gets an EGO boost.
Successful transporter gets an EGO boost.
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成功的运输者会增强自我意识。
DOI：
10.1016/j.devcel.2006.06.008
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发表时间：
2006
影响因子：
11.8
通讯作者：
Piper,RobertC
中科院分区：
文献类型：
--
作者：
Piper,RobertC
营养转运蛋白的运输受到多种信号转导途径的高度调节和控制。Gao和Kaiser（2006）在Nature Cell Biology中的一项最新研究证明了一种新的含GTP酶的复合物的作用，该复合物允许氨基酸通透酶Gap 1从晚期内体隔室中回收。这种复合物可能在允许动物细胞动员其营养转运蛋白以响应代谢需求方面发挥关键作用。
The trafficking of nutrient transporters is highly regulated and controlled by a variety of signal transduction pathways. A recent study by Gao and Kaiser (2006) inNature Cell Biologydemonstrates a role for a novel GTPase-containing complex that allows the amino acid permease Gap1 to recycle out of late endosomal compartments. This complex is likely to play critical roles in allowing animal cells to mobilize their nutrient transporters in response to metabolic demands.