Autosomal dominant polycystic kidney disease and transplantation.
Autosomal dominant polycystic kidney disease and transplantation.
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DOI：
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发表时间：
2009-12
影响因子：
1.1
通讯作者：
M. Niemczyk;S. Niemczyk;L. Pączek
中科院分区：
文献类型：
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作者：
M. Niemczyk;S. Niemczyk;L. Pączek
常染色体显性遗传性多囊肾病(ADPKD)是一种遗传性疾病，每1000人中就有1人患病，占终末期肾病(ESRD)病例的10%。除肾脏表现外，可能还会出现其他器官的变化。在没有禁忌症的情况下，患有ADPKD和ESRD的患者应该转诊到肾移植。ADPKD患者可能还需要肝移植或肝肾联合移植。此外，ADPKD患者可能成为潜在的器官捐赠者。本文的目的是回顾ADPKD患者移植前和移植后内科医生处理的问题。
Autosomal dominant polycystic kidney disease (ADPKD) is an inherited disorder affecting 1 in 1,000 people and responsible for 10% of cases of the end stage renal disease (ESRD). Apart from renal manifestations, changes in other organs may be present. In the absence of contraindications, patients with ADPKD and ESRD should be referred to renal transplantation. The ADPKD patient may also need liver transplantation, or combined liver and kidney transplantation. Also, the patient with ADPKD may become a potential organ donor. The aim of our paper is to review the problems that the physicians deal with in ADPKD patients in pre- and post-transplant period.