Complete Elimination of Cardiodepressant IgG3 Autoantibodies by Immunoadsorption in Patients With Severe Heart Failure
Complete Elimination of Cardiodepressant IgG3 Autoantibodies by Immunoadsorption in Patients With Severe Heart Failure
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DOI：
10.1253/circj.cj-09-0748
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发表时间：
2010-07-01
影响因子：
3.3
通讯作者：
Yoshikawa, Tsutomu
中科院分区：
文献类型：
--
作者：
Baba, Akiyasu;Akaishi, Makoto;Yoshikawa, Tsutomu
Background: Cardiodepressant IgG3 autoantibodies (CD-Abs) can be targeted by apheresis. Using blinded measurements of CD-Abs before and after immunoadsorption (IA), the cardiac function of patients who did or did not achieve complete CD-Abs elimination was compared.Methods and Results: Autoantibodies were completely removed from 18 patients with heart failure (New York Heart Assocation class 3 or 4, left ventricular ejection fraction (LVEF)
