DIFFERENT ORIGINS OF COCHLEAR EFFERENTS IN SOME BAT SPECIES, RATS, AND GUINEA-PIGS
DIFFERENT ORIGINS OF COCHLEAR EFFERENTS IN SOME BAT SPECIES, RATS, AND GUINEA-PIGS
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DOI：
10.1002/cne.902640106
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发表时间：
1987-10-01
影响因子：
2.5
通讯作者：
OSTWALD, J
中科院分区：
文献类型：
--
作者：
ASCHOFF, A;OSTWALD, J
用HRP和荧光染料固蓝逆行标记法研究了大鼠、豚鼠和蝙蝠的橄榄耳蜗传出神经的起源。除Rhinolophus rouxi外，所有物种的耳蜗传出神经都有两种类型：位于外侧上级橄榄（LSO）的小神经元和位于两侧橄榄周围区的大神经元。在蝙蝠和大鼠的小橄榄耳蜗神经元（OCN）被发现只在同侧LSO。在豚鼠中，在对侧LSO中也发现了一些小的OCN。除菊头蝠外，所有动物的OCN均较大。它们组织在一个马蹄形的核，在吻尾方向延伸，并在内侧上级橄榄（MSO）周围向吻侧弯曲。这个核包含几个由其他作者分别描述的橄榄周核。在Rhinol中，所有橄榄耳蜗传出神经的Rouxi胞体集中在MSO和LSO之间的单个核中，因此我们称之为橄榄耳蜗核。这个细胞核被乙酰胆碱酯酶染色。我们认为它的神经元类似于小OCN，因为它们很小，与LSO相关，并且仅同侧标记。这与菊头蝠缺乏外毛细胞的传出神经支配的事实非常吻合（Bisphop：Ph.D.论文，北卡罗来纳州大学，查佩尔山，'86;伯恩斯和Schmieszek;听。Res. 3：27-43，“80），其通常由大的OCN支配（Guinan等人：J. Comp. Neurol. 221：358-370，'' 83）。
The origin of olivocochlear efferents was studied in the rat, the guinea-pig, and the bats Rhinolophus, Rhinopoma, Tadarida, and Phyllostomus by retrograde labeling with HRP and the fluorescent dye fast blue. In all species with the exception of Rhinolophus rouxi two types of cochlear efferents could be found: small neurons located in the lateral superior olive (LSO) and larger ones located bilaterally in the periolivary region. In bats and rats small olivocochlear neurons (OCN) were found only in the ipsilateral LSO. In guinea-pigs some small OCN were found also in the contralateral LSO. Large OCN were found in all animals except Rhinolophus. They were organized in a horseshoelike nucleus that extended in a rostrocaudal direction and bent rostrally around the medial superior olive (MSO). This nucleus contains several periolivary nuclei described separately by other authors. In Rhinol, rouxi somata of all olivocochlear efferents are concentrated in a single nucleus between the MSO and LSO, which we therefore call the nucleus olivocochlearis. This nucleus stains for acetylcholinesterase. We consider its neurons to be similar to small OCN, because they are small, associated with the LSO, and only ipsilaterally labeled. This fits well with the fact that Rhinolophus lacks an efferent innervation of outer hair cells (Bisphop: Ph.D. Thesis, University of North Carolina, Chapel Hill, ''86; Burns and Schmieszek; Hear. Res. 3:27-43, ''80), which are normally innervated by large OCN (Guinan et al: J. Comp. Neurol. 221:358-370, ''83).