Factors influencing plasma zinc levels in low-income pregnant women

Factors influencing plasma zinc levels in low-income pregnant women
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DOI:
10.1007/bf02784174
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发表时间:
1996-10-01
影响因子:
3.9
通讯作者:
Hauth, JC
Hauth, JC
中科院分区:
生物学3区
文献类型:
--
作者:
Neggers, YH;Dubard, MB;Hauth, JC

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对 4376 名贫困妇女(86% 为非洲裔美国人)的平均 (+/- SD) 胎龄为 15 (+/- 7.8) 周的血浆锌 (Zn) 浓度进行了测量,以确定妊娠期间各种母亲特征与血浆锌水平之间的关系。非裔美国女性的平均血浆锌水平低于白人女性,经产女性低于初产女性,体重> 69.9公斤的女性低于体重小于或等于69.9公斤的女性(每次比较p小于或等于0.001)。母亲年龄、婚姻状况、教育程度或吸烟习惯没有显着差异。多元回归分析,包括母亲孕前体重、种族、年龄、胎次、吸烟习惯、教育程度和婚姻状况,表明种族、胎次和妊娠体重与母亲血浆锌水平显着相关,并根据胎龄进行调整。母亲种族是所研究的孕妇群体中血浆锌浓度的最佳预测因子。考虑到各种母亲特征后,母亲血浆锌水平的很大一部分差异仍然无法解释。与白人女性相比,非洲裔美国女性在怀孕期间血浆锌水平较低的原因尚不清楚。
Plasma zinc (Zn) concentrations were measured in 4376 indigent women (86% African-American), at a mean (+/- SD) gestational age of 15 (+/- 7.8) wk to determine the relationship between various maternal characteristics and plasma Zn levels during pregnancy. Mean plasma Zn levels were lower in African-American women than in Caucasian women, in multiparous women than in primiparous women, and in women with body weight > 69.9 kg than in those with body weight less than or equal to 69.9 kg (p less than or equal to 0.001 for each comparison). There were no significant differences related to maternal age, marital status, education, or smoking habit. Multiple regression analysis, including maternal prepregnacy weight, race, age, parity, smoking habit, education, and marital status indicated that race, parity, and pregnancy weight were significantly associated with maternal plasma Zn levels, adjusted for gestational age. Maternal race was the best predictor of plasma Zn concentrations among the population of pregnant women studied A significant proportion of variance in maternal plasma Zn levels remained unexplained after taking into account various maternal characteristics. The reasons for lower plasma Zn levels in African-American women, compared to Caucasian women, during pregnancy are unknown.