Innovative plAnt Protein fibre and Physical activity solutions to address poor appEtite and prevenT undernutrITion in oldEr adults - APPETITE
Innovative plAnt Protein fibre and Physical activity solutions to address poor appEtite and prevenT undernutrITion in oldEr adults - APPETITE
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DOI：
10.1111/nbu.12529
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发表时间：
2021-12-01
影响因子：
3.3
通讯作者：
Visser, Marjolein
中科院分区：
文献类型：
--
作者：
Volkert, Dorothee;Corish, Clare A.;Visser, Marjolein
由于食欲是食物摄入的关键驱动因素，食欲不佳的老年人营养不良的风险更高。膳食蛋白质和纤维是这一人群的重要营养素，增加其摄入量对于预防营养不良和维持器官功能和健康至关重要。在 APPETITE 项目中，来自六个欧洲国家八个机构的跨学科专家联盟将合作设计潜在有效的干预措施，以增加食欲不佳的社区老年人的蛋白质和纤维消耗，从而通过有针对性的营养和身体活动策略解决营养不良问题。首先将使用混合方法对食欲不佳的老年人进行评估，以深入了解他们的营养和行为偏好。与这一目标群体合作，将开发出结合了多种国内植物蛋白和膳食纤维的创新、可接受且负担得起的食品。通过检查所选产品和身体活动对消化率、氨基酸生物利用度和全身蛋白质代谢的影响，可以获得机理见解。在一项多国随机对照干预试验中，将确定作为个性化饮食、体育活动计划及其组合的一部分提供的两种新食品的影响。 APPETITE 将提高我们对植物蛋白和纤维产品及其代谢和临床效果的了解。它将创造新的知识，了解如何将这些产品与全饮食方法结合起来，再加上身体活动和定期的社交接触，以克服营养不良并为欧洲老年人提高生活质量做出贡献。
Older adults with poor appetite are at higher risk of undernutrition due to the role of appetite as a key driver of food intake. Dietary protein and fibre are critical nutrients in this population, and enhancing their intake is vital to preventing undernutrition and maintaining organ function and health. In APPETITE, a transdisciplinary consortium of experts from eight institutions in six European countries will collaborate to design potentially effective interventions to enhance protein and fibre consumption of community-dwelling older adults with poor appetite, thereby addressing undernutrition through a targeted nutrition- and physical activity-based strategy. Older adults with poor appetite will first be evaluated using a mixed-methods approach to gain insights into their nutritional and behavioural preferences. Working with this target group, innovative, acceptable and affordable food products will be developed that combine several domestic plant proteins and dietary fibres. Mechanistic insights will be gained by examining the impact of selected products and physical activity on digestibility, amino acid bioavailability and whole-body protein metabolism. In a multi-country, randomised controlled intervention trial, the impact of two new food products, provided as part of a personalised diet, a physical activity programme, and their combination will be determined. APPETITE will improve our understanding about plant-based protein and fibre products and their metabolic and clinical effects. It will create new knowledge about how these products can be combined in a whole-diet approach, together with physical activity and regular social contacts, to overcome undernutrition and to contribute to a better quality of life for older Europeans.