[Pulmonary lesion of paraquat poisoning on high resolution CT].
[Pulmonary lesion of paraquat poisoning on high resolution CT].
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发表时间：
1990-03
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通讯作者：
J. Kageyama;K. Satoh;Y. Kawase;K. Kojima;T. Tamai;M. Ohkawa;M. Tanabe;Y. Shirakawa;K. Oguri
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作者：
J. Kageyama;K. Satoh;Y. Kawase;K. Kojima;T. Tamai;M. Ohkawa;M. Tanabe;Y. Shirakawa;K. Oguri
众所周知，百草枯会导致严重的器官毒性和肺损伤。我们观察了一位百草枯中毒幸存者的病情进展，并通过高分辨率CT记录了肺部的变化。患者是一名35岁的男性，他服用百草枯（100毫升古拉莫酮）企图自杀。住院时，无呼吸系统受累。摄入后5天，X线检查仅显示两个肺野的血管分布不清，但高分辨率CT显示两个肺野中心部分的密度增加。根据摄入后的临床进展，胸部X线检查发现纵隔和皮下气肿。另一方面，通过高分辨率CT观察到重度间质性肺炎、重度肺纤维化进展伴肺体积减少和间质性肺气肿以及纵隔、皮下气肿。高分辨率CT有助于发现形态学改变和诊断临床分期。通过高分辨率CT观察变化过程有助于决定临床治疗过程，我们毫不犹豫地肯定它应该用于此类病例。
It is well known that paraquat causes severe organ-toxicity and pulmonary damage. We observed the progress of a patient who survived paraquat poisoning, and we recorded the changes in the lung by high resolution CT. The patient was a 35-year-old man who attempted suicide by paraquat (Guramoxone 100 ml) ingestion. At the time of hospitalization, there was no respiratory involvement. Five days after ingestion, an X-ray examination showed only indistinct vascularity of both lung fields, but high resolution CT showed increased density in the central part of both lung fields. According to the clinical progress after ingestion, mediastinal and subcutaneous emphysema were noted by chest X-ray examination. On the other hand, severe interstitial pneumonia progression of severe lung fibrosis with a decrease in lung volume and interstitial pulmonary emphysema in addition to mediastinal, subcutaneous emphysema were seen by high resolution CT. High resolution CT is useful for detecting morphologic change and diagnosing clinical stages. Observing the course of changes by high resolution CT is useful for deciding the course of clinical therapy, and we have no hesitation in affirming that it should be used in such cases.