Population-based study of chlamydial infection in China - A hidden epidemic
Population-based study of chlamydial infection in China - A hidden epidemic
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DOI：
10.1001/jama.289.10.1265
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发表时间：
2003-03-12
影响因子：
120.7
通讯作者：
Ng, KH
中科院分区：
文献类型：
--
作者：
Parish, WL;Laumann, EO;Ng, KH
背景下，性传播疾病在中国迅速增加。研究设计、背景与对象1999年8月至2000年8月在全国分层随机抽样调查了3426名20~岁的中国人，完成了计算机管理的调查，并提供了尿样(总参与率为69%)。结果衣原体或淋球菌感染的总阳性率为2.6%(95%可信区间[CI])，女性为1.6-4.1)，男性为2.1(95%CI，1.3-3.3)。对于淋球菌感染，女性每百人总患病率为0.08(95%可信区间，0.02-0.4)，男性为0.02(95%可信区间，0.005-0.1)。20~44岁男性衣原体感染的危险因素为与商业性工作者发生无保护的性行为(优势比为8.24；95%CI为3.51~19.35)、文化程度低(OR为7.20；95%CI为2.31~22.37)、最近与配偶或其他稳定性伴发生性行为(OR为7.73；95%CI为2.70~22.10)。在20-44岁的女性中，衣原体感染的危险因素是受教育程度较低(OR，2.82；95%CI，1.01-7.91)，居住在城市(OR，3.46；95%CI，1.67-7.18)或南部沿海(OR，2.16；95%CI，1.29-3.63)，以及有配偶或其他稳定的性伴侣，收入高(OR，2.85；95%CI，1.11-7.29)，经常社交(OR，2.79；95%可信区间为1.08~7.19)，或出行时间少于1周(OR=5.40；95%可信区间为1.44~20.3)。感染的模式表明了干预的潜在途径。
Context Sexually transmitted diseases are increasing rapidly in China. Surveillance data imperfectly indicate current prevalence and risk factors,Objectives To estimate the prevalence of genital chlamydial and gonococcal infections and to describe patterns of infection by subgroup and behavioral patterns.Design, Setting, and Participants A national stratified probability sample of 3426 Chinese individuals (1738 women and 1688 men) aged 20 to 64 years, who were interviewed between August 1999 and August 2000, completed a computer-administered survey, and provided a urine specimen (69% total participation rate).Main Outcome Measure Positive-test result for chlamydial or gonococcal infections.Results The overall prevalence per 100 population of chlamydial infection was 2.6 (95% confidence interval [CI], 1.6-4.1) for women and 2.1 (95% CI, 1.3-3.3) for men. For gonococcal infection, the overall prevalence per 100 population was 0.08 (95% CI, 0.02-0.4) for women and 0.02 (95% CI, 0.005-0.1) for men. Risk factors for chlamydial infection among men aged 20 to 44 years were unprotected sex with a commercial sex worker (odds ratio [OR], 8.24; 95% CI, 3.51-19.35), less education (OR, 7.20; 95% CI, 2.31-22.37), and recent sex with their spouse or other steady partner (OR, 7.73; 95% CI, 2.70-22.10). Among women aged 20 to 44 years, risk factors for chlamydial infection were having less education (OR, 2.82; 95% CI, 1.01-7.91) and living in a city (OR, 3.46; 95% CI, 1.67-7.18) or along the southern coast (OR, 2.16; 95% CI, 1.29-3.63) and having a spouse or other steady sexual partner who earned a high income (OR, 2.85; 95% CI, 1.11-7.29), who socialized often (OR, 2.79; 95% CI, 1.08-7.19), or who traveled less than 1 week per year (OR, 5.40; 95% CI, 1.44-20.3).Conclusions The prevalence of chlamydial infection in China is substantial. The patterns of infection suggest potential avenues for intervention.