Nanoscale studies of protein-membrane interactions in blood clotting.
Nanoscale studies of protein-membrane interactions in blood clotting.
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DOI:
10.1111/j.1538-7836.2011.04300.x
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发表时间:
2011-07
期刊:
影响因子:
--
通讯作者:
Rienstra CM
中科院分区:
文献类型:
--
作者:
Morrissey JH;Tajkhorshid E;Rienstra CM
Most of the steps in the blood clotting cascade require clotting proteins to bind to membrane surfaces with exposed phosphatidylserine. In spite of the importance of these protein-membrane interactions, we still lack a detailed understanding of how clotting proteins interact with membranes and how membranes contribute so profoundly to catalysis. Our laboratories are using multidisciplinary approaches to explore, at atomic-resolution, how blood clotting protein complexes assemble and function on membrane surfaces.
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影响因子:
2.9
作者:
Boettcher, John M.;Davis-Harrison, Rebecca L.;Clay, Mary C.;Nieuwkoop, Andrew J.;Ohkubo, Y. Zenmei;Tajkhorshid, Emad;Morrissey, James H.;Rienstra, Chad M.
通讯作者:
Rienstra, Chad M.
DOI:
10.1073/pnas.062565599
发表时间:
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作者:
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通讯作者:
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通讯作者:
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