Establishment of the LNCaP Cell Line - The Dawn of an Era for Prostate Cancer Research.
Establishment of the LNCaP Cell Line - The Dawn of an Era for Prostate Cancer Research.
复制标题
建立LNCAP细胞系 - 前列腺癌研究时代的曙光。
DOI：
10.1158/0008-5472.can-22-1065
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发表时间：
2022-05-03
期刊：
影响因子：
11.2
通讯作者：
中科院分区：
文献类型：
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作者：
Among the relatively few established human prostate cancer cell lines, LNCaP cells are unique in their ability to model key stages of prostate cancer progression. Analyses of LNCaP cells and their derivatives have been invaluable for elucidating important translational aspects of prostate tumorigenesis, metastasis, and drug response, particularly in the context of androgen receptor signaling. Here we present major highlights from a wealth of literature that has exploited LNCaP cells and their derivatives to inform on prostate cancer progression and androgen response for improving the treatment of prostate cancer patients.
