Monoamine oxidase and cigarette smoking
Monoamine oxidase and cigarette smoking
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DOI：
10.1016/s0161-813x(02)00109-2
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发表时间：
2003-01-01
期刊：
影响因子：
3.4
通讯作者：
Volkow, ND
中科院分区：
文献类型：
--
作者：
Fowler, JS;Logan, J;Volkow, ND
目前的吸烟者已经减少了单胺氧化酶(MAO)，有证据表明，这是烟草烟雾暴露的药理效应，而不是吸烟者的生物学特征。本文综述了有关烟草烟雾对MAO的抑制作用的人类和动物研究，并从吸烟流行病学、烟草中MAO抑制剂化合物、精神疾病中低血小板MAO的再调查和戒烟等方面对MAO的抑制进行了讨论。(C)2002 Elsevier Science Inc.保留所有权利。
Current cigarette smokers have reduced monoamine oxidase (MAO) and there is evidence that this is a pharmacological effect of tobacco smoke exposure rather than a biological characteristic of smokers. This article summarizes human and animal studies documenting the inhibitory effects of tobacco smoke on MAO and discusses MAO inhibition in the context of smoking epidemiology, MAO inhibitor compounds in tobacco, reinvestigations of low platelet MAO in psychiatric disorders and smoking cessation. (C) 2002 Elsevier Science Inc. All rights reserved.