Small solutions for big problems: the application of nanoparticles to brain tumor diagnosis and therapy.

Small solutions for big problems: the application of nanoparticles to brain tumor diagnosis and therapy.
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DOI:
10.1038/clpt.2008.296
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发表时间:
2009-05
影响因子:
6.7
通讯作者:
--
中科院分区:
医学2区
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--
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纳米颗粒可能在未来中枢神经系统恶性肿瘤的诊断和治疗中发挥关键作用。纳米颗粒有可能彻底改变术前和术中脑肿瘤检测。此外,纳米粒子还可以作为化疗、基因疗法、光动力疗法和热疗法的新型靶向递送装置。将纳米技术的当前研究转化为脑肿瘤治疗的临床相关组成部分将依赖于解决与纳米颗粒药理学相关的挑战。
Nanoparticles are likely to play a key role in the future diagnosis and treatment of CNS malignancies. Nanoparticles have the potential to revolutionize both preoperative and intraoperative brain tumor detection. In addition, nanoparticles may also serve as novel, targeted delivery devices for chemotherapy, gene therapy, photodynamic therapy and thermotherapy. The translation of current research in nanotechnology into a clinically relevant component of brain tumor management will rely on solving challenges related to the pharmacology of nanoparticles.
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