Synthesis and characterization of poly(glycerol-succinic acid) dendrimers
Synthesis and characterization of poly(glycerol-succinic acid) dendrimers
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DOI：
10.1021/ma010848n
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发表时间：
2001-10-23
期刊：
影响因子：
5.5
通讯作者：
Grinstaff, MW
中科院分区：
文献类型：
--
作者：
Carnahan, MA;Grinstaff, MW
介绍了由甘油和丁二酸组成的新型树枝状大分子的合成方法。这些“生物树枝状聚合物”完全由已知为生物相容性的或在体内可降解为天然代谢物的结构单元组成，并且使用高产率发散方法制备。此外，所采用的合成策略适合于新材料的设计和开发，如通过连接可光聚合基团所证明的。
The syntheses of novel dendrimers composed of glycerol and succinic acid are described. These "biodendrimers" are composed entirely of building blocks known to be biocompatible or degradable in vivo to natural metabolites and are prepared using a high yield divergent approach. Moreover, the synthetic strategy employed is amenable to the design and development of new materials as demonstrated by the attachment of a photopolymerizable group.