Evolution of parasite virulence against qualitative or quantitative host resistance
Evolution of parasite virulence against qualitative or quantitative host resistance
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DOI：
10.1098/rspb.2000.1100
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发表时间：
2000-05-22
影响因子：
4.7
通讯作者：
Michalakis, Y
中科院分区：
文献类型：
--
作者：
Gandon, S;Michalakis, Y
我们分析了两种不同的宿主抗性模式对寄生虫毒力进化的影响。寄生虫可以采取全有或全无的定性反应（即抗性宿主不能被感染）或定量形式的抗性（即降低寄生虫在宿主内的生长速度）。我们表明，宿主的抗性模式极大地影响了进化的结果。具体而言，定性形式的抗性降低寄生虫的毒力，而定量形式的抗性通常选择更高的毒力。
We analysed the effects of two different modes of host resistance on the evolution of parasite virulence. Hosts can either adopt an all-or-nothing qualitative response (i.e. resistant hosts cannot be infected) or a quantitative form of resistance (i.e. which reduces the within-host growth rate of the parasite). We show that the mode of host resistance greatly affects the evolutionary outcome. Specifically, a qualitative form of resistance reduces parasite virulence, while a quantitative form of resistance generally selects for higher virulence.