STATIC MECHANICAL-PROPERTIES OF DEVELOPING AND MATURE RAT AORTA
STATIC MECHANICAL-PROPERTIES OF DEVELOPING AND MATURE RAT AORTA
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DOI：
10.1093/cvr/9.5.669
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发表时间：
1975-01-01
影响因子：
10.8
通讯作者：
RIVETT, JF
中科院分区：
文献类型：
--
作者：
BERRY, CL;GREENWALD, SE;RIVETT, JF
作者对4周龄至2岁大鼠的主动脉静态力学特性进行了研究。在1.33~33.3 kPa(10~250 mm Hg)压力范围内，测量了内径、相对壁厚、周向增量应变和周向增量弹性模量值。结果表明，12周后增量弹性模量值基本不变。在年轻动物身上观察到的变化与相对壁厚的变化有关。这一发现与先前观察到的化学和形态变化相关联。肌肉功能研究表明，中层的平滑肌肉对血管壁的静态弹性特性没有显著贡献。
AUTHORS' SYNOPSISThe static mechanical properties of the aorta have been examined in rats, aged between 4 weeks and 2 years. Internal radius, relative wall thickness, circumferential incremental strain, and circumferential incremental elastic modulus have been measured at pressures between 1.33 and 33.3 kPa (10 and 250 mm Hg). The results show that the value of the incremental elastic modulus does not change after 12 weeks. Changes observed in younger animals are related to alterations in relative wall thickness. The findings correlate with previously observed chemical and morphological changes.Studies of muscle function indicate that the smooth muscle of the media does not contribute significantly to the static elastic properties of the vessel wall.