Is the long-term decline in cardiovascular-disease mortality in high-income countries over? Evidence from national vital statistics

Is the long-term decline in cardiovascular-disease mortality in high-income countries over? Evidence from national vital statistics
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DOI:
10.1093/ije/dyz143
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发表时间:
2019-12-01
影响因子:
7.7
通讯作者:
Adair, Tim
Adair, Tim
中科院分区:
医学1区
文献类型:
--
作者:
Lopez, Alan D.;Adair, Tim

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工作背景:在过去的半个世纪里,高收入国家心血管疾病(CVD)死亡率的大幅下降支撑了他们不断增长的寿命。然而,最近的证据表明,这种长期下降可能已经停滞,甚至在年轻人口中逆转。我们评估最近的心血管疾病死亡率的趋势,在高收入人群中,并讨论了有关的危险factors.Methods的趋势的研究结果:我们使用的生命统计数据,自2000年以来,23个高收入国家发表在世界卫生组织死亡率数据库。使用LOWESS回归计算并平滑所有年龄段和35-74岁年龄段按性别划分的标准化CVD死亡率。调查结果进行了对比与全球疾病负担(GBD)Study.Results:近年来,在大多数国家,无论是男性还是女性,尤其是在35-74岁年龄段,心血管疾病死亡率的下降速度已经大大放缓。根据最近一年的数据,35-74岁年龄段的心血管疾病死亡率下降,
Background: The substantial decline in cardiovascular-disease (CVD) mortality in high-income countries has underpinned their increasing longevity over the past half-century. However, recent evidence suggests this long-term decline may have stagnated, and even reversed in younger populations. We assess recent CVD-mortality trends in high-income populations and discuss the findings in relation to trends in risk factors.Methods: We used vital statistics since 2000 for 23 high-income countries published in the World Health Organization Mortality Database. Age-standardized CVD death rates by sex for all ages, and at ages 35-74 years, were calculated and smoothed using LOWESS regression. Findings were contrasted with the Global Burden of Disease (GBD) Study.Results: The rate of decline in CVD mortality has slowed considerably in most countries in recent years for both males and females, particularly at ages 35-74 years. Based on the latest year of data, the decline in the CVD-mortality rate at ages 35-74 years was