Brucellosis as a cause of acute febrile illness in Egypt
Brucellosis as a cause of acute febrile illness in Egypt
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DOI：
10.1016/j.trstmh.2007.02.027
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发表时间：
2007-07-01
影响因子：
2.2
通讯作者：
Mahoney, Francis J.
中科院分区：
文献类型：
--
作者：
Jennings, Gregory J.;Hajjeh, Rana A.;Mahoney, Francis J.
为了更好地估计布鲁氏菌病的发病率，我们在两个夏季（2002年和2003年）在埃及法尤姆省（人口2 347 249）进行了以人口为基础的急性发热性疾病（AFI）监测。所有医院和社区供热供应商的代表性样本都包括在内。无明显病因的AFI患者通过培养和血清学检测布鲁氏菌病。计算发生率估计值，调整采样方法和研究期。在入组的4490例AFI患者中，321例（7%）符合布鲁氏菌病病例定义。年度估计。2002年和2003年每10万人口中布鲁氏菌病发病率分别为64和70。布鲁氏菌病患者的中位年龄为26岁，70%为男性; 53%最初被诊断为伤寒。与动物密切接触和食用未经巴氏消毒的奶制品与布鲁氏菌病有关。法尤姆布鲁氏菌病的高发病率突出了其公共卫生的重要性，以及在人类和动物中实施预防战略的必要性。(C)2007年皇家热带医学和卫生学会。由爱思唯尔有限公司出版。保留所有权利。
To develop better estimates of brucellosis incidence, we conducted population-based surveillance for acute febrile illness (AFI) in Fayoum governorate (population 2 347 249), Egypt during two summer periods (2002 and 2003). All hospitals and a representative sample of community heatthcare providers were included. AFI patients without obvious etiology were tested for brucellosis by culture and serology. Incidence estimates were calculated adjusting for sampling methodology and study period. Of 4490 AFI patients enrolled, 321 (7%) met the brucellosis case definition. The estimated annual. incidence of brucellosis per 100 000 population was 64 and 70 in 2002 and 2003, respectively. The median age of brucellosis patients was 26 years and 70% were male; 53% were initially, diagnosed as typhoid fever. Close contact with animals and consumption of unpasteurized milk products were associated with brucellosis. The high incidence of brucellosis in Fayoum highlights its public health importance, and the need to implement prevention strategies in humans and animals. (C) 2007 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.