Unimolecular micelle derived from hyperbranched polyethylenimine with well‐defined hybrid shell of poly(ethylene oxide) and polystyrene: A versatile nanocapsule
Unimolecular micelle derived from hyperbranched polyethylenimine with well‐defined hybrid shell of poly(ethylene oxide) and polystyrene: A versatile nanocapsule
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DOI：
10.1002/pola.23821
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发表时间：
2010-02
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影响因子：
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通讯作者：
Yong Liang;Decheng Wan;Xiangyu Cai;M. Jin;H. Pu
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文献类型：
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作者：
Yong Liang;Decheng Wan;Xiangyu Cai;M. Jin;H. Pu
描述了由超支化聚乙烯亚胺 (HPEI) 衍生的大分子纳米胶囊的合成和性能，该纳米胶囊具有明确的聚环氧乙烷单甲醚 (mPEO) 和聚苯乙烯 (PS) 混合壳。 HPEI依次用4-缩水甘油-2,2,6,6-四甲基-哌啶-1-氧基、琥珀酸酐、mPEO处理，产生与硝基氧介导的苯乙烯活性自由基聚合相容的HPEI衍生物，因此可得到具有明确且可调节的PEO和PS混合壳的大分子纳米胶囊HPEI@PEO/PS。在一定的PEO/PS比例下，纳米胶囊可溶于多种有机溶剂以及水。纳米胶囊在水中以三层洋葱状颗粒（HPEI@PS@PEO）存在，而在氯仿中以杂化壳颗粒（HPEI@PEO/PS）存在，且颗粒一般以单分子胶束形式存在。在水/氯仿双相混合物中，纳米胶囊可以将阴离子、水溶性客体从水相转移到氯仿相；当溶解在水中时，纳米胶囊可以有效捕获离子和非极性溶质。客体的释放可以在pH值的刺激或介质的转换下发生。这是第一个可以同时传递极性和非极性客体的单分子胶束的例子。 © 2009 Wiley periodicals, Inc. J Polym Sci Part A：Polym Chem 48：681–691，2010
The synthesis and properties of a macromolecular nanocapsule derived from hyperbranched polyethylenimine (HPEI) with well-defined hybrid shell of poly(ethylene oxide) monomethyl ether (mPEO) and polystyrene (PS) are described. HPEI is treated in sequence with 4-glycidol-2,2,6,6-tetrametyl-piperidin-1-oxyl, succinic anhydride, mPEO, leading to a HPEI derivative compatible with nitroxide-mediated living radical polymerization of styrene, thus a macromolecular nanocapsule, HPEI@PEO/PS, is available with a well-defined and tunable hybrid shell of PEO and PS. Within certain PEO/PS ratio, the nanocapsule is soluble in a number of organic solvents as well as in water. The nanocapsule exists as three layer onion-like particle (HPEI@PS@PEO) in water, whereas in chloroform it exists as a hybrid shell particle (HPEI@PEO/PS), and the particles generally exist in the form of unimolecular micelle. In a biphasic water/chloroform mixture, the nanocapsule can transfer anionic, water-soluble guest from an aqueous phase to the chloroform phase; while when dissolved in water, the nanocapsule can efficiently capture both ionic and apolar solutes. Release of the guest can occur under the stimulus of pH or the switch of medium. This is the first example of a unimolecular micelle that can simultaneously deliver both polar and apolar guests. © 2009 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 48: 681–691, 2010