AUTONOMIC CHARACTERISTICS OF NONCLINICAL PANIC AND BLOOD PHOBIA
AUTONOMIC CHARACTERISTICS OF NONCLINICAL PANIC AND BLOOD PHOBIA
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DOI：
10.1016/0006-3223(93)90087-t
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发表时间：
1993-09-01
影响因子：
10.6
通讯作者：
COLUMBO, R
中科院分区：
文献类型：
--
作者：
FRIEDMAN, BH;THAYER, JF;COLUMBO, R
使用心电图（EKG）频谱分析以及更传统的心血管测量方法来比较非临床恐慌症和血液恐惧症的自主神经特征。记录了 11 名最近频繁发生严重惊恐发作的受试者和 10 名报告看到血就出现强烈躯体反应（包括晕厥发作）的受试者在各种实验室任务（安静休息、反应时间/避免电击、面部浸入以及综合反应时间/面部浸入）期间的心血管反应。结果表明，各组的自主神经模式不同。恐慌者表现出（a）较高的心率和较低的心率变异性（b）心血管指标之间的异常关联，以及（c）交感神经对心率的主导控制加上迷走神经张力减弱。血液恐惧症通常表现出相反的模式。讨论了这些发现与恐慌症和血液恐惧症的病因学以及一般焦虑症的生物学模型的相关性。
Autonomic characteristics of nonclinical panic and blood phobia were compared using spectral analysis of the electrocardiogram (EKG), as well as more conventional cardiovascular measures. The cardiovascular responses of 11 subjects who reported recent occurrence of frequent severe panic attacks, and 10 subjects who reported intense somatic reactions to the sight of blood (including episodes of syncope) were recorded during a variety of laboratory tasks (quiet rest, reaction time/shock avoidance, face immersion, and combined reaction time/face immersion). Results suggest distinct autonomic patterns in the groups. Panickers showed (a) higher heart rate and reduced heart-rate variability (b) aberrant associations among cardiovascular measures, and (c) dominant sympathetic control of heart rate coupled with diminished vagal tone. Blood phobics generally displayed an opposite pattern. The relevance of these findings to the etiology of panic and blood phobia, as well as to biological models of anxiety disorders in general, is discussed.