High oolong tea consumption predicts future risk of diabetes among Japanese male workers: a prospective cohort study
High oolong tea consumption predicts future risk of diabetes among Japanese male workers: a prospective cohort study
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DOI：
10.1111/j.1464-5491.2011.03239.x
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发表时间：
2011-07-01
影响因子：
3.5
通讯作者：
Ueshima, H.
中科院分区：
文献类型：
--
作者：
Hayashino, Y.;Fukuhara, S.;Ueshima, H.
乌龙茶的急性给药降低血糖水平。我们调查了长期乌龙茶的摄入量和随后的风险之间的关联发展糖尿病的男性workingage.Methods数据进行了分析，从一个队列的参与者在高风险和人口战略职业健康促进研究（HIPOP-OHP），在日本进行，从1999年至2004年。乌龙茶的摄入量在基线和随后的糖尿病风险进行了评估，使用考克斯比例风险model.Results的4975名男性工人，共有201例糖尿病报告超过中位数为3.4年的后续行动。所有参与者基线时的平均年龄和BMI分别为38.3岁和22.9 kg/m2。与不喝乌龙茶的人相比，每天喝一杯乌龙茶的人患糖尿病的多变量校正风险比为1.00（95%CI 0.67-1.49），每天喝两杯或两杯以上的人为1.64（95%CI 1.11-2.40）。每年空腹血糖增量为0.11 mmol/ l（95% CI 0.09-0.12 mmol/l），0.12 mmol/l（95% CI 0.09-0.15 mmol/l）和0.15 mmol/l（95% CI 0.11-0.18 mmol/l），分别为乌龙茶消费量0、1和>= 2杯/天，结论长期饮用乌龙茶可能是新发糖尿病的一个预测因素。进一步的研究是必要的，以阐明乌龙茶在发展糖尿病的风险中的作用。
Aims Acute administration of oolong tea decreases blood glucose levels. We investigated the association between long-term oolong tea intake and subsequent risk of developing diabetes among men of working age.Methods Data were analysed from a cohort of participants in the High-risk and Population Strategy for Occupational Health Promotion Study (HIPOP-OHP), conducted in Japan from 1999 to 2004. Oolong tea intake at baseline and subsequent risk of diabetes was evaluated using a Cox proportional hazards model.Results Of 4975 male workers, a total of 201 cases of diabetes were reported over a median of 3.4 years of follow-up. Mean age and BMI of all participants at baselinewere 38.3 years and 22.9 kg/m(2), respectively. Compared with those not consuming oolong tea, multivariable adjusted hazard ratios for developing diabetes were 1.00 (95% CI 0.67-1.49) for those who drank one cup of oolong tea per day and 1.64 (95% CI 1.11-2.40) for those drinking two or more cups per day. Fasting blood glucose increment per year was 0.11 mmol/ l (95% CI 0.09-0.12 mmol/l), 0.12 mmol/l (95% CI 0.09-0.15 mmol/l) and 0.15 mmol/l (95% CI 0.11-0.18 mmol/l), respectively, for oolong tea consumption of 0, 1 and >= 2 cups/day, with a significant linear trend (P < 0.0001).Conclusions Long-term consumption of oolong tea may be a predictive factor for new onset diabetes. Further studies are necessary to elucidate the role of oolong tea in the risk of developing diabetes.