The potential economic value of a hookworm vaccine
The potential economic value of a hookworm vaccine
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DOI：
10.1016/j.vaccine.2010.12.004
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发表时间：
2011-02-01
期刊：
影响因子：
5.5
通讯作者：
Smith, Kenneth J.
中科院分区：
文献类型：
--
作者：
Lee, Bruce Y.;Bacon, Kristina M.;Smith, Kenneth J.
钩虫感染是一个世界性的重大问题。随着钩虫疫苗的开发，疫苗开发商和制造商、政策制定者和其他公共卫生官员了解这种疫苗的潜在成本和好处是至关重要的。我们开发了一个决策分析模型来评估将钩虫疫苗引入巴西两个人群的成本效益：学龄儿童和育龄非怀孕妇女。结果表明，疫苗不仅会节省成本，而且对两个人群都有潜在的健康益处。事实上，最具成本效益的干预策略可能是将疫苗与当前的药物治疗策略相结合。(C)2010爱思唯尔有限公司。保留所有权利。
Hookworm infection is a significant problem worldwide. As development of hookworm vaccine proceeds, it is essential for vaccine developers and manufacturers, policy makers, and other public health officials to understand the potential costs and benefits of such a vaccine. We developed a decision analytic model to evaluate the cost-effectiveness of introducing a hookworm vaccine into two populations in Brazil: school-age children and non-pregnant women of reproductive age. Results suggest that a vaccine would provide not only cost savings, but potential health benefits to both populations. In fact, the most cost-effective intervention strategy may be to combine vaccine with current drug treatment strategies. (C) 2010 Elsevier Ltd. All rights reserved.