Why is psychogenic nonepileptic seizure diagnosis missed? A retrospective study
Why is psychogenic nonepileptic seizure diagnosis missed? A retrospective study
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DOI：
10.1016/j.yebeh.2019.06.001
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发表时间：
2019-08-01
影响因子：
2.6
通讯作者：
Asadi-Pooya, Ali A.
中科院分区：
文献类型：
--
作者：
Bahrami, Zahra;Homayoun, Maryam;Asadi-Pooya, Ali A.
Purpose: The aim of this retrospective study was to scrutinize factors that are associated with a delay in making the diagnosis of psychogenic nonepileptic seizures (PNES).Methods: In this study, patients with PNES, who were investigated at Shiraz Comprehensive Epilepsy Center, Iran, from 2008 to 2019, were studied. We categorized the patients into the following: 1. those with a definite diagnosis of PNES in less than a year since the onset of their attacks; 2. those with a definite diagnosis of PNES later than 10 years since the onset of their attacks.Results: During the study period, 330 patients were recorded. In 98 patients (30%), the diagnosis of PNES was made in less than a year since their seizure onset. In 67 patients (20%), the diagnosis of PNES was made later than 10 years since their seizure onset. Taking antiepileptic drugs (AEDs) (odds ratio (OR) = 6) and a history of ictal injury (OR = 3.6) had a positive association, and age at the onset (OR = 0.8) had an inverse association with a delay in receiving a definite diagnosis of PNES (p = 0.0001).Conclusion: Some demographic variables (i.e., early age at the onset of seizures), patients' dinical variables (i.e., severe seizure manifestations such as ictal injury), and finally, some physician-related variables (i.e., prescribing AEDs) have significant associations with a delay in making a definite diagnosis of PNES. (C) 2019 Elsevier Inc. All rights reserved.
