A short cervix in women with preterm labor and intact membranes: A risk factor for microbial invasion of the amniotic cavity
A short cervix in women with preterm labor and intact membranes: A risk factor for microbial invasion of the amniotic cavity
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DOI：
10.1016/j.ajog.2004.10.624
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发表时间：
2005-03-01
影响因子：
9.8
通讯作者：
Gonzalez, R
中科院分区：
文献类型：
--
作者：
Gomez, R;Romero, R;Gonzalez, R
目的：本研究的目的是确定超声检查宫颈长度与培养证实的早产且膜完整的女性羊水腔微生物入侵之间是否存在关系。研究设计：对401名早产（22-35周）且宫颈扩张小于或等于3厘米的入院患者进行超声检查和羊水穿刺术。通过手指检查评估。入院时通过经阴道超声确定宫颈长度。结果变量是存在微生物侵入羊膜腔（定义为羊水培养阳性）和35周前早产的发生。结果：401例患者中，羊膜腔微生物感染的发生率为7%（28/401）。21.4%（82/384）的患者发生自发性早产（≤ 35周）。ROC曲线分析显示，羊膜腔微生物侵袭频率与宫颈长度有显著相关性（曲线下面积：0.77; P
Objective: The purpose of this study was to determine whether there was a relationship between sonographic cervical length and the presence of culture-proven microbial invasion of the ammotic cavity in women with preterm labor and intact membranes.Study design: Ultrasonography and amniocentesis were performed in 401 patients admitted with preterm labor (22-35 weeks) and cervical dilatation of less than or equal to 3 cm. as assessed by digital examination. Cervical length was determined by transvaginal ultrasound at admission. Outcome variables were the presence of microbial invasion of the amniotic cavity (defined as a positive amniotic fluid culture) and the occurrence of preterm delivery before 35 weeks. Contingency tables x(2) test, receiver-operator characteristic (ROC) curves, and logistic regression were used for statistical analysis.Results: The prevalence of microbial invasion of the amniotic cavity was 7% (28/401). Spontaneous preterm delivery (less than or equal to 35 weeks) occurred in 21.4% (82/384) of patients. ROC curve analysis showed a significant relationship between the frequency of microbial invasion of the ammotic cavity and the length of the uterine cervix (area under the curve: 0.77; P