Discovery and understanding of transition-metal-catalyzed aromatic substitution reactions
Discovery and understanding of transition-metal-catalyzed aromatic substitution reactions
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DOI：
10.1055/s-2006-939728
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发表时间：
2006-06-01
期刊：
影响因子：
2
通讯作者：
Hartwig, John F.
中科院分区：
文献类型：
--
作者：
Hartwig, John F.
本文介绍了芳基卤化物和磺酸盐与胺、醇盐和各种烯醇酸盐的交叉偶联反应的研究进展。重点介绍了利用作者实验室获得的机理信息开发新型催化剂的过程。1介绍2早期反应开发3新催化剂开发4交叉偶联过程的机理5氧化加成机理6胺的还原消除7伯胺偶联的稳定钯催化剂8催化剂选择指南。
This article presents studies on the development of cross-coupling reactions of aryl halides and sulfonates with amines, alkoxides, and various enolates. Emphasis is placed on the process of developing new catalysts with mechanistic information gained in the author's laboratory.1 Introduction2 Early Reaction Development3 New Catalyst Developments4 Mechanism of the Cross-Coupling Processes5 Mechanism of Oxidative Addition6 Reductive Elimination of Amines7 Stable Palladium Catalysts for Coupling of Primary Amines8 Guidelines for Catalyst Selection.