Reparative bone-like tissue formation in the tooth of a systemic sclerosis patient

Reparative bone-like tissue formation in the tooth of a systemic sclerosis patient
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DOI:
10.1111/iej.12914
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发表时间:
2018-09-01
影响因子:
5
通讯作者:
Kurihara, H.
Kurihara, H.
中科院分区:
医学2区
文献类型:
--
作者:
Matsuda, S.;Memida, T.;Kurihara, H.

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目的报告一例系统性硬化症患者牙齿修复性骨样组织形成的病例。摘要一例58岁的日本女性系统性硬化症患者因牙齿骨折而被转诊。锥形束计算机断层扫描(CBCT)显示多个牙根吸收以及从牙槽骨到牙根轮廓的过渡不清楚。对一颗断裂牙齿的样本进行了组织学分析。苏木精和伊红染色切片显示牙髓和牙本质被骨样组织不规则替代。在身体的各个部位发现钙质沉着,组织学分析将其鉴定为硬化纤维结缔组织上的营养不良性钙化。咬合力和咬合面积明显弱于同龄女性的平均值。关键学习点CBCT可能比牙科X线片更有助于诊断系统性硬化症患者的多发性牙根吸收。当系统性硬化症患者有钙质沉着时,必须仔细检查其牙根状态。当系统性硬化症患者存在牙根吸收时,在开始牙科治疗之前,需要考虑牙齿中的修复性骨样组织形成。
AimTo report a case of reparative bone-like tissue formation in the tooth of a patient with systemic sclerosis.SummaryA 58-year-old Japanese female patient with systemic sclerosis was referred because of tooth fracture. Cone beam computerized tomography (CBCT) revealed multiple root resorption and the unclear transition from alveolar bone to root profile. A sample from a fractured tooth was analysed histologically. Haematoxylin and eosin-stained sections revealed the irregular replacement of pulp and dentine by bone-like tissue. Calcinosis was noted in various parts of the body and a histological analysis identified it as dystrophic calcification on sclerosed fibrous connective tissue. Bite force and the occlusal area were markedly weaker than the means for female of the same age.Key learning pointsCBCT may be more useful than dental radiography for diagnosing multiple root resorption in systemic sclerosis patients.When systemic sclerosis patients have calcinosis, their root status must be examined carefully.When root resorption is present in systemic sclerosis patients, reparative bone-like tissue formation in teeth needs to be taken into account prior to the initiation of dental treatment.