NEW METHODS OF DRUG DELIVERY
NEW METHODS OF DRUG DELIVERY
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DOI：
10.1126/science.2218494
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发表时间：
1990-09-28
期刊：
影响因子：
56.9
通讯作者：
LANGER, R
中科院分区：
文献类型：
--
作者：
LANGER, R
传统的给药方式通常依赖于药片、眼药水、药膏和静脉溶液。最近，一些新的给药方法被开发出来。这些方法包括通过化学手段对药物进行修饰，将药物包裹在注入血管的小泡中，以及将药物包裹在泵或聚合物材料中，这些材料被放置在所需的身体区域（例如，眼睛或皮肤下）。这些技术已经导致了改善人类健康的输送系统，继续研究可能会彻底改变许多药物的输送方式。
Conventional forms of drug administration generally rely on pills, eye drops, ointments, and intravenous solutions. Recently, a number of novel drug delivery approaches have been developed. These approaches include drug modification by chemical means, drug entrapment in small vesicles that are injected into the bloodsteram, and drug entrapment within pumps or polymeric materials that are placed in desired bodily compartments (for example, the eye or beneath the skin). These techniques have already led to delivery systems that improve human health, and continued research may revolutionize the way many drugs are delivered.