Examining the role of nutrition support and outcomes for hospitalized patients: putting nutrition back in the study design.
Examining the role of nutrition support and outcomes for hospitalized patients: putting nutrition back in the study design.
复制标题
检查住院患者营养支持的作用和结果：将营养重新纳入研究设计中。
DOI：
10.1016/j.jada.2010.08.019
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发表时间：
2010
影响因子：
--
通讯作者：
Peterson,SarahJ
中科院分区：
文献类型：
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作者：
Braunschweig,CarolA;Sheean,PatriciaM;Peterson,SarahJ
40多年来，非自愿喂养（即肠内营养[EN]和肠外营养[PN]）的使用一直是注册营养师（RD）用于胃肠道功能受限或无胃肠道功能的住院患者的医学营养治疗的支柱。到目前为止，这种疗法的使用仍然存在一些争议，一些临床医生认为其风险和成本超过了其益处。本评论将探讨将PN或EN与标准治疗（即正常、自愿的饮食摄入）进行比较的前瞻性随机临床试验的结果，引用可能出现这些结果的具体原因，并讨论RD可以为优化这些类型研究的研究设计提供的潜在贡献。
For more than 40 years the use of nonvolitional feedings (ie, enteral nutrition [EN] and parenteral nutrition [PN]) has been a mainstay of the medical nutrition therapy that registered dietitians (RDs) utilize for their hospitalized patients with limited or no gastrointestinal function. To date, the use of this therapy remains somewhat controversial, and some clinicians dispute that its risks and costs outweigh its benefits. This commentary will explore the findings of prospective randomized clinical trials that compared PN or EN to standard care (ie, normal, volitional dietary intake), cite specific reasons why these findings may have occurred, and discuss the potential contribution the RD can provide to optimize study designs for these types of investigations.