[Some important clinical aspects of cytomegalovirus infection].
[Some important clinical aspects of cytomegalovirus infection].
复制标题
[巨细胞病毒感染的一些重要临床方面]。
DOI：
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发表时间：
1998
期刊：
影响因子：
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通讯作者：
S. Chiba
中科院分区：
文献类型：
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作者：
S. Chiba
未标记
本文从临床角度讨论了人巨细胞病毒（CMV）感染的一些重要方面。先天性感染：目前，对孕妇进行大规模筛查的理由并不充分，主要是因为检测胎儿感染的诊断方法价值有限，而且缺乏有效的预防措施。广泛的诊断方法和宫内治疗可能适用于宫内发育迟缓或异常超声检查结果的情况下。
诊断和治疗
外周血白细胞中病毒抗原的显示已被证明是一个有用的工具，用于监测器官移植受者的CMV疾病的早期诊断，及时应用抗病毒治疗和评估治疗的效果。然而，这种方法不是一个有效的支持检测CMV疾病由于围产期感染。
未来前景
未来的研究前景可能包括调查慢性CMV感染在病因不明的疾病中可能的致病作用，如糖尿病、神经系统疾病、缺血性心脏病、自身免疫性疾病或癌症，特别是宫颈癌、前列腺癌和直肠癌。
UNLABELLED
Some important aspects of human cytomegalovirus (CMV) infection were discussed from a clinical point of view. Congenital infection: The mass-screening of pregnant women is not justified at present, mainly because of limited value of diagnostic methods for detecting fetal infection and unavailability of effective measure for prevention. Extensive diagnostic approach and intrauterine therapy may be applicable in the case of intrauterine growth retardation or abnormal ultrasonographic findings.
DIAGNOSIS AND TREATMENT
The demonstration of viral antigens in peripheral blood leukocytes has been proven to be a useful tool for monitoring organ transplant recipients for the early diagnosis of CMV disease, timely application of antiviral therapy and evaluating the efficacy of the treatment. However, this method is not a valid support for detecting CMV disease due to perinatal infection.
FUTURE PROSPECTS
FUTURE PROSPECTS of research may include investigations for the possible pathogenic role of chronic CMV infection in diseases of unknown etiology such as diabetes mellitus, neurological disorders, ischemic heart disease, autoimmune diseases, or cancers especially in cervix, prostate and rectum.