Resolution of Racemic Jasmonic Acid and Abscisic Acid by Chiral High Performance Liquid Chromatography
Resolution of Racemic Jasmonic Acid and Abscisic Acid by Chiral High Performance Liquid Chromatography
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DOI：
10.1002/(sici)1099-1565(199607)7:4
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发表时间：
1996-07
影响因子：
3.3
通讯作者：
R. Kramell;G. Schneider;O. Miersch
中科院分区：
文献类型：
--
作者：
R. Kramell;G. Schneider;O. Miersch
报道了外消旋茉莉酸(JA)和脱落酸(ABA)作为游离酸，在Nucleodexβ-PM柱上直接拆分成相应的对映体。该方法的拆分因子为RsJA=1.38，RsABA=1.65，可用于制备规模的外消旋分离。茉莉酸甲酯及其12-羟基衍生物的外消旋体可以被拆分为它们各自的甲酯。用圆二色谱和旋光色散对得到的纯异构体进行了表征。
The direct resolution of racemic jasmonic acid (JA) and abscisic acid (ABA), as the free acids, into the corresponding enantiomers by high performance liquid chromatography on a Nucleodex β-PM column is reported. The resolution factors (Rs JA=1.38; Rs ABA=1.65) were such that the method could be applied to the separation of these racemates on a preparative scale. The racemates of methyl jasmonate and its 12-hydroxy-derivative could be resolved as their respective methyl esters. The pure isomers obtained were characterized using circular dichroism and optical rotatory dispersion.